Work with our scientists!
3 artist-in-residence opportunities
We are seeking 3 artists who are eager to work with the research groups specialized in DNA replication, cell fates and cancer research. The Artist in Residence programme involves specifically the younger generation: the PhD students in the RepliFate Marie-Curie network
In case of any questions, reach out to: replifate@cbm.csic.es
Take a look at the three themes!
We offer 3 individual artist-in-residence spots to connect with the research in the RepliFate network
In the RepliFate doctoral network, 12 fellows (PhD students) work in 12 laboratories throughout Europe researching DNA replication as a target for cancer treatment and stem cell identity. Each fellow works on a well-defined project within one of the four workpackages of the RepliFate research project – addressing questions ranging from fundamental research in genetics to exploration in drug development. For the artist-in-residence programme, the fellows are grouped in three themes. These themes give artists the opportunity to propose artistic projects and artistic research approaches that they aim to realize in the course of a residency with one selected theme, but with the opportunity to interact with the other themes across the network.
Faces of Stress and Malignance
How does stress manifest and what are the responses of our cells to stress? How is it related to malignance in cells? What are opportunities to address stress for drug development?
This theme brings together the research of four partners in the RepliFate network who look at ways in which stress impacts cellular development, such as cell fate, mutations, or genome instability, and looks at how cells respond to stress, for example, by changing their epigenetic layout. Importantly, knowledge about faces of stress in cellular replication and their entanglement with malignance in cell reproduction helps the researchers to find ways to address malignance through new drugs.
The artist will engage with methods and knowledge from the fields of cell and molecular biology, including imaging using microscopy on live cells and CRISPR technology.
Main partners in the RepliFate network are:
(In)Stability and Damage Repair
What are the structures that provide stability and instability in cell responses to stress? How to regulate stability and instability? Can such knowledge be employed to explore opportunities for damage repair?
This theme integrates research into structural studies into the regulation of DNA replication and into how the DNA can be repaired by the DNA damage response that the cells possess. This theme is combined with research based on structures of proteins that is used towards cancer therapeutics. Questions of cell fate decisions, responses to replication stress, pathways and factors that play a role in these processes, and understanding of molecular modulators in the cells are researched by the fellows in this theme.
The artist will engage with methods and knowledge from the fields of structural biology and biochemistry, including mass-spectrometry to identify unknown proteins and computational biology, data integration and bioinformatics.
Main partners in the RepliFate network are:
Transformation through Replication
How is replication and the duplication of our DNA connected to transformation? How are cell fates defined during this duplication processes? What changes when replications are produced under stress? What is the connection of replication stress for inflammatory responses and cancer?
The researchers in this theme apply new imaging techniques in genetics and functional genomics research to understand the dynamics and organization of DNA duplication as well as cell differentiation. They are also interested in unveiling the relevance of replication processes for the development of cancer and cell fates, to ask whether the duplication of the DNA itself drives the process of cell differentiation. They are interested in the composition of the replication machinery and transformation processes in cells, and the impact of replication dynamics on healthy and malignant cell cycles.
The artist will engage with methods and knowledge from the fields of molecular biology, including single DNA molecule studies, epigenetics, stem cells and computational biology.
Main partners in the RepliFate network are: